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. 2016 Oct 10;35(4):619–629. doi: 10.1002/hon.2325

Table 1.

Treatment protocol for MESA chemotherapy

Agent Dose Per Day Route Day of Administrationa
Methotrexate 2 g/m2 IV 1
Etoposide 100 mg/m2 VD 2, 3, 4,
Dexamethasone 20 mg/m2 VD 2, 3, 4, 5
Polyethylene glycol‐asparaginase 2500 IU/m2 IM 5

Cycles were repeated every 21 days. Three courses were planned as the protocol treatment.

Abbreviations: IM, intramuscular; IU, international units; IV, intravenous; MESA, methotrexate, etoposide, dexamethasone, polyethylene glycol‐asparaginase; VD, intravenous drip.