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. 2017 Dec 21;11(Suppl 7):133. doi: 10.1186/s12918-017-0509-y

Table 3.

Example of gene pairs which are molecularly non-interacting but dynamically influential (MNDI)

Network Gene pairs Sub-graph μ(v i, v j) l(v i, v j)
AMRN EMF1, AG EMF1→ TFL1⊣ AG 0.146 2
TFL1, AP1 TFL1⊣ LFY→ AP1 0.0125 2
ABAN ABA, S1P ABA→ SphK→ S1P 0.498 2
ABA, NIA12 ABA→ RCN1→ NIA12 0.498 2
HSN CSK, BCR CSK⊣ LYN→ BCR 0.503 2
GHR, IGF1R GHR→ IGF1→ IGF1R 0.382 2

Source and target genes are represented by orange- and green-colored nodes, respectively. Sub-graph field means the shortest path with respect to the gene pair in the GMI network. Arrow-headed (→) and bar-headed (⊣) lines indicate activating (positive) and inhibitory (negative) interactions, respectively