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. 2017 Sep 20;8(Suppl 1):32. doi: 10.1186/s13326-017-0141-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Illustrative example of SNF steps. (a) Gene-gene similarity matrices based on CC and MF ontology, respectively. (b) Gene functional similarity networks. Genes are represented by nodes and pairwise similarities between genes are represented by edges. (c) Network fusion by SNF updates iteratively, making them more similar with each step. (d) The iterative network fusion results in convergence to the final integrated network. Edge color indicates which data type has contributed to the given similarity