Table 1.
Neuropsychological function | Test |
---|---|
Episodic memory |
Free and Cued Selective Reminding Test (FCSRT)a
Logical memory and Paired associative learning from Wechsler memory scale (WMS)a Brief visuospatial memory test (BVMT) total recalla |
Working memory |
Digit span forward, from Wechsler Adult Intelligence Scale (WAIS) IIIb
Digit span backwards, from Wechsler Adult Intelligence Scale (WAIS) IIIb |
Attention | Trail Making Test (TMT) Ac and Bc |
Verbal function |
Controlled Oral Word Association (COWA) Boston Naming Test (BNT) |
Visuospatial function |
The Benton Judgement of Line Orientation testd
Pentagon copying from Mini‐Mental State Examination (MMSE) |
Executive function |
Wisconsin card sorting test (WCST) – computer version 2e
Mental Control from Wechsler memory scale (WMS) Category fluency (animals in 60 seconds)e |
A domain score was calculated by the mean of standardized scores (Z‐scores) in the tests of episodic memorya, working memoryb, attentionc, visuospatial functiond, and executive functione.
Subjects were classified as having mild cognitive impairment (PD‐MCI) if: (i) impaired in a minimum of two tests in one domain (single domain MCI) or in a minimum of one test in two different domains (multiple domain MCI), (ii) impairments were ≥1.5 standard deviations below mean of normative data, (iii) self‐perceived cognitive decline was reported by Questionnaire and/or directly by patient and/or family member, and (iv) no functional impairment in basic activities of living.
Parkinson's disease dementia (PDD) diagnoses were based on neuropsychological test results, objective and subjective cognitive decline, and by the occurrence of functional impairment in basic activities of living (ie, driving a car, social or personal care, medication management) due to cognitive decline.