Table 2.

Effects of exogenous glucose and corticosterone on METH‐induced FJc⁺ labeling/neurodegeneration

Treatment group	Parietal cortex	PV nucleus thalamus	VM, VL & IL nuclei thalamus	Sample sizea
Saline	0.39 ± 0.13	0.21 ± 0.07	0.29 ± 0.09	5
Glucose	0.18 ± 0.06	0.09 ± 0.06	0.01 ± 0.01	5
CORT	0.25 ± 0.09	0.10 ± 0.07	0.02 ± 0.01	5
METH	6.40 ± 0.62	5.03 ± 0.72	53.31 ± 11.18	6
METH+glucose	8.22 ± 1.01	16.11 ± 4.66	85.00 ± 24.03	6
METH+CORT	18.14 ± 1.39b	6.54 ± 1.18	69.59 ± 13.26	7
METH+Veh	8.58 ± 1.25	2.67 ± 0.39	14.87 ± 2.88	6

Mean ± SEM of FJc⁺/section/hemisphere are shown.

^aThe number of animals per group evaluated is less than expected by 2–3 animals per treatment group from the mortality loss shown in Table 1. This is because animals that did not reach 41.7°C body temperatures were excluded from analysis.

^bIndicates neurodegeneration was significantly different than each of the other METH groups.