Table 2.
Visit | IOP (mmHg) | IOP change from baseline (mmHg) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline | 4 weeks | 8 weeks | 4 weeks | 8 weeks | ||||||
Time | 9 AM | 11 AM | 9 AM | 11 AM | 9 AM | 11 AM | 9 AM | 11 AM | 9 AM | 11 AM |
BTFC | ||||||||||
N | 92 | 92 | 91 | 91 | 90 | 90 | 91 | 91 | 90 | 90 |
Mean | 17.4 | 17.0 | 14.4 | 13.9 | 14.0 | 13.5 | −3.1 | −3.0 | −3.5 | −3.5 |
SD | 2.1 | 1.8 | 2.3 | 2.2 | 2.3 | 2.0 | 1.9 | 1.9 | 1.9 | 1.9 |
Minimum | 15.0 | 15.0 | 8.0 | 8.0 | 8.0 | 9.0 | −8.5 | −8.0 | −8.0 | −9.0 |
Maximum | 25.0 | 22.0 | 20.0 | 20.5 | 22.0 | 21.0 | 2.0 | 2.0 | 1.0 | 3.0 |
DTFC | ||||||||||
N | 97 | 97 | 96 | 96 | 97 | 97 | 96 | 96 | 97 | 97 |
Mean | 17.3 | 17.0 | 14.6 | 13.6 | 14.3 | 13.5 | −2.7 | −3.3 | −3.0 | −3.4 |
SD | 1.8 | 1.7 | 2.1 | 2.0 | 2.1 | 1.9 | 2.0 | 2.0 | 2.0 | 2.0 |
Minimum | 15.0 | 15.0 | 10.0 | 9.0 | 10.0 | 9.0 | −7.0 | −9.0 | −7.0 | −9.5 |
Maximum | 22.0 | 22.0 | 21.0 | 19.0 | 20.0 | 18.0 | 3.0 | 4.0 | 2.0 | 3.0 |
IOP = Intraocular pressure; BTFC = brinzolamide timolol fixed combination; DTFC = dorzolamide timolol fixed combination; SD = standard deviation.