Table 3.
Asthma occurrence in the various time periods (logistic regression for the SLIT tablet group vs the non‐AIT group)
| Factors | Odds ratio | 95% CI | P‐value |
|---|---|---|---|
| Treatment period | |||
| Intercept | 0.063 | 0.044‐0.092 | <.001 |
| SLIT treatment (vs control) | 0.714 | 0.547‐0.932 | .013 |
| Age <18 y (vs age 18+ y) | 1.102 | 0.963‐1.260 | .159 |
| Male (vs unknown) | 0.875 | 0.803‐0.952 | .002 |
| Female (vs unknown) | 1.068 | 0.984‐1.159 | .117 |
| ENT specialist (vs GP) | 0.681 | 0.631‐0.736 | <.001 |
| Dermatologist (vs GP) | 1.054 | 0.838‐1.325 | .654 |
| Pneumologist (vs GP) | 2.898 | 2.314‐3.630 | <.001 |
| Paediatrician (vs GP) | 1.472 | 1.182‐1.832 | .001 |
| Internal specialist (vs GP) | 0.977 | 0.880‐1.084 | .659 |
| Other speciality (vs GP) | 1.125 | 0.837‐1.514 | .435 |
| Number of years SLIT treatment (p.a.) | 0.813 | 0.664‐0.994 | .044 |
| Level of AR treatment before index | 0.977 | 0.965‐0.990 | <.001 |
| Length of individual observation period | 1.752 | 1.569‐1.957 | <.001 |
| Follow‐up period | |||
| Intercept | 0.018 | 0.008‐0.040 | <.001 |
| SLIT treatment (vs control) | 0.575 | 0.372‐0.888 | .013 |
| Age <18 y (vs age 18+ y) | 0.868 | 0.729‐1.033 | .110 |
| Male (vs unknown) | 0.805 | 0.728‐0.890 | <.001 |
| Female (vs unknown) | 0.984 | 0.893‐1.085 | .751 |
| ENT specialist (vs GP) | 0.820 | 0.750‐0.896 | <.001 |
| Dermatologist (vs GP) | 0.742 | 0.530‐1.038 | .082 |
| Pneumologist (vs GP) | 2.136 | 1.550‐2.943 | <.001 |
| Paediatrician (vs GP) | 0.930 | 0.664‐1.302 | .672 |
| Internal specialist (vs GP) | 1.010 | 0.892‐1.143 | .876 |
| Other speciality (vs GP) | 1.282 | 0.924‐1.779 | .138 |
| Number of years SLIT treatment (p.a.) | 0.981 | 0.679‐1.418 | .919 |
| Level of AR treatment before index | 1.014 | 1.000‐1.027 | .049 |
| Length of individual observation period | 1.311 | 1.252‐1.372 | <.001 |
| Full analysis period (treatment+follow‐up) | |||
| Intercept | 0.044 | 0.030‐0.064 | <.001 |
| SLIT treatment (vs control) | 0.696 | 0.552‐0.877 | .002 |
| Age <18 y (vs age 18+ y) | 0.973 | 0.872‐1.085 | .620 |
| Male (vs unknown) | 0.835 | 0.781‐0.893 | <.001 |
| Female (vs unknown) | 1.024 | 0.960‐1.093 | .470 |
| ENT specialist (vs GP) | 0.738 | 0.696‐0.784 | <.001 |
| Dermatologist (vs GP) | 0.905 | 0.746‐1.099 | .313 |
| Pneumologist (vs GP) | 2.655 | 2.181‐3.232 | <.001 |
| Paediatrician (vs GP) | 1.257 | 1.042‐1.517 | .017 |
| Internal specialist (vs GP) | 0.991 | 0.912‐1.076 | .827 |
| Other speciality (vs GP) | 1.178 | 0.937‐1.480 | .161 |
| Number of years SLIT treatment (p.a.) | 1.089 | 0.922‐1.285 | .315 |
| Level of AR treatment before index | 0.998 | 0.989‐1.008 | .720 |
| Length of individual observation period | 1.202 | 1.166‐1.240 | <.001 |
AIT, allergen immunotherapy; AR, allergic rhinitis; SLIT, sublingual immunotherapy.