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Effect of commensal bacteria on PLP91–110 induced EAE in HLA-DR3.DQ8 transgenic mice
| Treatment | Disease incidence (%) | Disease free, Mean ± SE, daysA | Hazard ratio (95% CI) | p-value |
|---|---|---|---|---|
| Medium fed | 20/20 (100%) | 10.6 ± 0.2 | 1 (ref) | |
| P. histicola | 5/20 (25%) | 17.5 ± 0.3 | 0.03 (0.01–0.09) | <0.0001 |
| C. sputigena | 20/20 (100%) | 11.4 ± 0.4 | 0.6 (0.3–1.2) | 0.15 |
| P. melaninogenica | 16/20 (80%) | 12.5 ± 0.4 | 0.2 (0.1 –0.5) | <0.0009 |
| E. coli | 20/20 (100%) | 11 ± 0.3 | 0.8 (0.4 – 0.6) | 0.47 |
Estimated by the log-rank test
