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. Author manuscript; available in PMC: 2018 Jan 11.
Published in final edited form as: Cancer Lett. 2017 Oct 9;411:171–181. doi: 10.1016/j.canlet.2017.09.045

Fig. 3.

Fig. 3

1,25(OH)2D-Mediated Regulation of the Pentose Phosphate Pathway. MCF10A-ras cells were treated with vehicle or 1,25(OH)2D (10 nM). (A) G6PD mRNA was measured after 48 h of treatment and is expressed relative to vehicle treated cells. (B) Proportion of PPP to glycolytic glucose flux was measured after 96 h of treatment. (C) Intracellular ribose-5-phosphate concentration was measured after 96 h of treatment and is expressed as ng/mg protein. (D) MCF10A-ras cells were treated with vehicle or 1,25(OH)2D for 96 h with a concurrent DHEA treatment for the last 24 h. ROS values are expressed relative to vehicle treated cells with no DHEA (0 μM). All values are presented as mean ± S.E.M. Asterisk (*) indicates significant difference from vehicle (P < 0.05). Bars with different letters are significantly different (P < 0.05).