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. 2018 Jan 10;12:3. doi: 10.1186/s12918-017-0524-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The heatmap of the subset 407 DEGs identified in the meta-analysis. For each DEG, its normalized expression value in each sample of the nine datasets was indicated in the heatmap. Two hundred forty one genes were up-regulated and 166 genes were down-regulated. The genes were clustered using the Ward’s method [56]. The samples were grouped first by comparison group then by individual studies