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. 2018 Jan 10;12:3. doi: 10.1186/s12918-017-0524-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Protein-protein interaction network of the 1655 DEGs in the meta-analysis. a The subnetwork of all DEGs including their functional partners. Each node represents a gene and each edge represents an interaction between two genes supported by experimental evidence. The up-regulated genes were colored in red. The down-regulated genes were colored in green. The non-DEG functional partners were colored in grey. The minimum network mode was chosen for display purposes. b The subnetwork of only DEGs exclusive of their functional partners