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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: FEBS Lett. 2017 Oct 27;591(21):3548–3554. doi: 10.1002/1873-3468.12867

Table 1A.

13C fractional enrichments of GLU C4 in the tumors. Calculation of a–e are from 13C NMR spectra of C4 GLU as described in the text (Materials and Methods). d and e correspond to the fractions that have [4,5-13C] and [3,4,5-13C] isotopomers respectively. a is the fraction that has no 13C. (b+c) together represents the contributions from the metabolism of [1,2-13C]acetate by peripheral organs to tumor GLU C4 13C pool. FE is equal to (b+c+d+e) and corresponds to fractional enrichment of GLU C4 in the tumor.

Tumor type a b c d e FE (b+c)/FE (d+e)/FE
GBM 0.758 0.014 0.002 0.188 0.038 0.242 0.066 0.934
GBM 0.717 0.024 0.003 0.222 0.035 0.283 0.094 0.906
Breast metastasis 0.537 0.017 0.006 0.354 0.087 0.464 0.050 0.950
Lung metastasis 0.554 0.019 0.006 0.339 0.083 0.446 0.056 0.944