Table V.
Complications of 43 Patients with Asparaginase-Associated VTE
| All patients | Paediatrics | Adults | |
|---|---|---|---|
|
| |||
| Total | 43 | 27 | 16 |
|
| |||
| Anticoagulation Complications | |||
| Bruising | 1 (2%) | 0 (0%) | 1 (6%) |
| Epistaxis | 4 (9%) | 2 (7%) | 2 (13%) |
| Major Bleeding1 | 2 (5%) | 0 (0%) | 2 (13%) |
|
| |||
| VTE Complications | |||
| Postphlebitic Syndrome | 3 (7%) | 0 (0%) | 3 (19%) |
| Chronic Headaches | 6 (14%) | 4 (15%) | 2 (13%) |
| Catheter Removal | 9 (21%) | 4 (15%) | 4 (25%) |
|
| |||
| Restarted Asparaginase | 33 (77%) | 20 (74%) | 13 (81%) |
|
| |||
| VTE Recurrence | 11 (26%) | 4 (15%) | 7 (44%) |
|
| |||
| Deaths from VTE | 0 (0%) | 0 (0%) | 0 (0%) |
1
Major bleeding: 1 intracranial hemorrhage, 1 compartment syndrome after bone marrow aspirate