Table 2.
Association between TLR polymorphisms and hepatitis activity
| Genotype | Mild chronic hepatitis | Moderate and severe chronic hepatitis | Odds Ratio (95%CI) |
|---|---|---|---|
| Number (%) | Number (%) | ||
| rs1075993 | |||
| TT | 83(55.0) | 25(41.7) | 1(Ref.) |
| CT | 64(42.4) | 32(53.3) | 1.66(0.90–3.08) |
| CC | 4(2.6) | 3(5.0) | 2.49(0.52–11.88) |
| rs3804099 | |||
| TT | 60(39.7) | 41(68.3) | 1(Ref.) |
| CT | 50(33.1) | 15(25.0) | 0.44(0.22–0.89)a |
| CC | 41(27.2) | 4(6.7) | 0.14(0.05–0.43)a |
| rs4696480 | |||
| CC | 83(55.0) | 25(41.7) | 1(Ref.) |
| CT | 64(42.4) | 32(53.3) | 0.98(0.48–1.98) |
| TT | 4(2.6) | 3(5.0) | 0.35(0.15–0.80)a |
a P < 0.05