Table 1.
Mean (SD) values for the primary and secondary outcomes at each assessment during the baseline and intervention periods
| Outcome | Baseline period | Intervention period | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Assessment 1 | Assessment 2 | Assessment 3 | Assessment 4 | Assessment 5 | ||||||
| N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | |
| Rett Syndrome Gross Motor Scale (/45) | 12 | 22.7 (9.6) | 12 | 22.4 (10.4) | 12 | 25.5 (8.9) | 12 | 27.6 (8.4) | 12 | 29.8 (9.7) |
| Blood Brain Derived Neurotrophic Factor (ng/ml) | 11 | 165.0 (28.8) | 12 | 146.1 (50.1) | – | – | – | – | 10 | 510.0 (104.2) |
| BMI | 12 | 15.2 (1.4) | 12 | 15.1 (1.5) | 12 | 14.6 (1.0) | 11 | 14.7 (1.5) | 11 | 15.0 (1.6) |
| Sleep Disturbance Scale for Children (DIMS subscale, /35)* | 12 | 15.8 (5.5) | 12 | 16 (6.1) | 12 | 15.6 (4.3) | 11 | 15.4 (7.2) | 11 | 14.4 (5.6) |
| Rett Syndrome Behaviour Questionnaire (Mood subscale, /16)* | 12 | 8.6 (3.6) | 12 | 7 (3.6) | 12 | 7.6 (3.6) | 11 | 7.3 (3.0) | 11 | 8.7 (3.5) |
*One child unwell at assessment 4 and another at assessment 5