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. Author manuscript; available in PMC: 2018 Jan 11.
Published in final edited form as: Diabetes Metab Res Rev. 2016 Apr 21;32(7):736–744. doi: 10.1002/dmrr.2794

Table 2.

Prevalence of Baseline Electrocardiographic Abnormalities by Quartile of OGTT or HOMA Parameters

Quartile 1 [range] Quartile 2 [range] Quartile 3 [range] Quartile 4 [range] p value a
OGTT-derived MISIb [0.35–1.66] [1.68–2.48] [2.49–3.73] [3.76–14.69]
 LVH (%) 4.0 1.7 2.3 1.1 0.12
 Q (%) 15.3 8.6 8.0 6.3 0.005
 ST-T (%) 16.5 18.3 18.2 20.0 0.42
OGTT-derived IGIb [0.003–0.10] [0.11–0.24] [0.25–0.48] [0.49–7.58]
 LVH (%) 2.8 1.2 4.0 1.1 0.66
 Q (%) 11.3 7.5 7.4 12.0 0.84
 ST-T (%) 22.0 21.3 13.1 16.0 0.04
HOMA-IR [0.58–2.92] [2.93–4.36] [4.39–7.09] [7.11–47.72] e
[0.51–2.84] [2.85–4.27] [4.28–6.73] [6.75–47.72] f
 LVH (%)
  OGTT Subsampleb 0.6 3.4 1.1 4.5 0.06
  Total Samplec 1.0 2.3 2.3 5.4 <0.001
 Q (%)
  OGTT Subsampleb 6.7 7.3 10.1 13.6 0.018
  Total Samplec 6.4 4.8 7.6 10.1 0.007
 ST-T (%)
  OGTT Subsampleb 15.7 20.3 18.5 17.5 0.78
  Total Samplec 17.4 17.3 19.5 21.2 0.08
HOMA-Bd [14.53–66.46] [66.58–106.24] [106.40–175.59] [175.84–6480.00] e
[14.53–61.41] [61.57–100.15] [100.22–167.53] [168.00–3204.00] f
 LVH (%)
  OGTT Subsample 2.3 1.1 4.5 1.7 0.74
  Total Sample 3.3 1.7 3.1 2.9 0.96
 Q (%)
  OGTT Subsample 7.9 9.6 9.0 11.3 0.32
  Total Sample 6.8 6.8 7.2 8.0 0.45
 ST-T (%)
  OGTT Subsample 21.9 19.8 14.6 15.8 0.07
  Total Sample 19.8 18.1 19.7 17.8 0.59
a

Statistical significance was tested using nonparametric test for trend across ordered groups, an extension of the Wilcoxon rank-sum test.

b

OGTT Subsample n=710;

c

Total Sample n=1671

d

Participants on insulin therapy were excluded for analyses of HOMA-B leaving n=1334 for Total sample and n=554 for OGTT subsample

e

Quartile ranges for participants in OGTT subsample

f

Quartile ranges for participants in the total sample

Abbreviations: HOMA-IR=homeostatic model assessment of insulin resistance, HOMA-B=homeostatic model assessment of beta-cell function