Fig. 7.

Summary of the levels of NR2A-containing NMDARs, NR2B-containing NMDARs, and drebrin at postsynaptic versus cytoplasmic locations reported for spines belonging to hippocampi of ABA-vulnerable and ABA-resilient individuals. The strongly correlating pools of synaptic proteins are shown as putatively interacting through direct contacts. The correlations suggest that the inactive pool of cytoplasmic NR2A level is actively retained from becoming inserted into the PSD through interaction with drebrin, and that drebrin interacts relatively more strongly with NR2B-containing NMDARs at the PSD than with NR2A-containing NMDARs