Table 2. Average values obtained from CON tissue for each of the subcellular domains of each antigen.
Presynaptic | Postsynaptic | Extra-synaptic post | Cytoplasmic post | Anywhere pre | Anywhere post | Anywhere pre/post | ||
---|---|---|---|---|---|---|---|---|
NR2A | PEG particle number, per 10 synapses | 0.839 ± 0.107 | 1.822 ± 0.229 | 0.232 ± 0.032 | 0.729 ± 0.135 | 2.446 ± 0.269 | 2.783 ± 0.332 | 5.229 ± 0.589 |
Proportion of spines labeled, per 10 synapses | 0.692 ± 0.088 | 1.446 ± 0.182 | 0.203 ± 0.025 | 0.543 ± 0.075 | 1.765 ± 0.179 | 2.090 ± 0.222 | 3.571 ± 0.304 | |
NR2B | PEG particle number, per 10 synapses | 0.892 ± 0.084 | 2.082 ± 0.341 | 0.281 ± 0.043 | 1.363 ± 0.266 | 3.433 ± 0.397 | 3.725 ± 0.569 | 7.158 ± 0.928 |
Proportion of spines labeled, per 10 synapses | 0.806 ± 0.076 | 1.700 ± 0.268 | 0.246 ± 0.028 | 1.033 ± 0.166 | 2.429 ± 0.230 | 2.722 ± 0.370 | 4.407 ± 0.425 |
Data represent the mean ± SEM