Table 4.
Factors independently influencing OS in multivariable analysis.
| Factor | HR | 95% CI | p-Value |
|---|---|---|---|
| Prior thrombocytopenia | 2.184 | 1.208–3.951 | 0.01 |
| Age (per year increase) | 1.018 | 0.996–1.040 | 0.12 |
| UKMRC adverse karyotype (versus intermediate) | 1.942 | 1.193–3.161 | 0.008 |
| Treatment with low-intensity agents (versus supportive care only) | 0.186 | 0.090–0.385 | <0.0001 |
| Treatment with induction chemotherapy (versus supportive care only) | 0.138 | 0.058–0.326 | <0.0001 |
| Treatment with stem cell transplant | 0.331 | 0.186–0.591 | <0.0001 |