Table 1.
Pathological findings.
| Group | Pig no. | Gross-pathological lesions | Scores–lungsA | Swine influenza virus-like lesions |
|---|---|---|---|---|
| 800 μg DNA/vacc. | 1 | No apparent lesions | 0 | None |
| 2 | Small consolidated areas (multifocal) in left median lobe | 0 | None | |
| 3 | Minimal consolidation foci in the left lobe | 0 | None | |
| 4 | No apparent lesions | 0 | None | |
| 5 | No apparent lesions | 0 | None | |
| 500 μg DNA/vacc. | 5 | Very minimal consolidation foci right cranial lobe and left median lobe | 0.5 | Very mild broncho-interstitial pneumonia |
| 7 | Small consolidated areas in right median lobe and cranial portion of right diaphragmatic lobe | 0.5 | Very mild broncho-interstitial pneumonia | |
| 8 | No apparent lesions | 0 | None | |
| 9 | Minimal consolidation areas/foci in the left medium and right cranial lobes | 0.5 | Very mild broncho-interstitial pneumonia | |
| 10 | No apparent lesions | 0 | None | |
| No vaccine | 11 | Lung consolidation in right median lobe and more areas in both cranial lobes | 1.5 | Mild-to-moderate broncho-interstitial pneumonia |
| 12 | Small consolidation areas in both median lobes | 2 | Moderate broncho-interstitial pneumonia | |
| 13 | Consolidation areas in right median and left median lobes and cranial areas of left diaphragmatic lobe | 0 | None | |
| 14 | Small areas of consolidation in the right apical lobe | 0.5 | Very mild broncho-interstitial pneumonia | |
| 15 | Very small areas of multifocal consolidation in the right apical lobe and moderate extensive areas in the left middle lobe | 1.5 | Mild-to-moderate broncho-interstitial pneumonia | |
A
Scoring system of lung lesions by influenza in pigs according to Detmer et al. (2013) 0, No airways affected; 0.5, Only a few isolated airways affected; 1, Localized cluster of affected airways (in 1 or 2 lobes); 1.5, Several airways affected throughout section plus minimal interstitial infiltrates; 2, Several airways affected throughout section plus mild to moderate interstitial infiltrates; 2.5, Several airways affected, often severely, plus moderate interstitial and alveolar infiltrates; 3, Many airways affected, often severely, plus moderate interstitial and alveolar infiltrates.