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. 2018 Jan 8;11:1178646917751636. doi: 10.1177/1178646917751636

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Maturation-dependent increase in IDO activity in IFN-γ–activated human monocyte/macrophages from a single donor. Human mononuclear phagocytic cells from a single donor cultured for 0 or 10 days were exposed to IFN-γ at a final concentration of 10, 100, or 600 U/mL for either 24 or 48 hours. IDO activity was determined on the cell homogenate. A dose- (IFN-γ), time-, and maturation-dependent increase in IDO activity was observed. *P < .05; **P < .01; ***P < .001 (n = 4-12). Statistics used was the Tukey-Kramer analysis of variance. IDO indicates indoleamine 2,3-dioxygenase.