Table 6.
Hierarchal Linear Regressions in a priori regions of interest using linear and quadratic age. Bilateral dorsal and ventral lateral prefrontal cortex regions of interest defined by 8 mm sphere around the peak within that region from the Label > Blur contrast (at p < 0.0001, k ≥ 14). Medial orbital frontal cortex and bilateral amygdala regions of interest defined by 8 mm sphere around the peak within that region from the View > Blur contrast (at p < 0.0001, k ≥ 14).
Hierarchical Linear Regression | R2 | Δ in R2 | B | β | t | p |
---|---|---|---|---|---|---|
Medial Orbital Frontal Cortex | ||||||
age linear. | 0.09 | 0.09 | −0.06 | −0.29 | 3.27 | 0.03 |
age quadratic | 0.09 | 0.00 | 0.00 | 0.05 | −2.23 | 0.70 |
Right Ventral Lateral Prefrontal Cortex | ||||||
age linear | 0.01 | 0.01 | 0.01 | 0.10 | 0.76 | 0.45 |
age quadratic | 0.08 | 0.07 | 0.008 | 0.27 | 2.05 | 0.05 |
Right Dorsal Lateral Prefrontal Cortex | ||||||
age linear | 0.03 | 0.03 | 0.02 | 0.19 | 1.48 | 0.14 |
age quadratic | 0.08 | 0.05 | <0.01 | 0.22 | 1.73 | 0.08 |
Left Dorsal Lateral Prefrontal Cortex | ||||||
age linear | <0.01 | <0.01 | <0.01 | 0.09 | 0.66 | 0.51 |
age quadratic | 0.02 | 0.02 | 0.004 | 0.13 | 0.99 | 0.33 |
Left Ventral Lateral Prefrontal Cortex | ||||||
age linear | 0.01 | 0.01 | −0.01 | −0.08 | −0.63 | 0.53 |
age quadratic | 0.07 | 0.06 | 0.01 | 0.24 | 1.82 | 0.08 |
Left Amygdala | ||||||
age linear | 0.03 | 0.03 | −0.01 | −0.16 | −1.18 | 0.24 |
age quadratic | 0.03 | 0.001 | 0.001 | 0.03 | 0.24 | 0.81 |
Right Amygdala | ||||||
age linear | 0.01 | 0.01 | 0.01 | 0.12 | 0.86 | 0.40 |
age quadratic | 0.01 | <0.01 | <0.01 | 0.03 | 0.23 | 0.82 |