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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Bone. 2017 Jun 7;103:1–11. doi: 10.1016/j.bone.2017.06.004

Figure 4. OIM mice have increased osteoclast progenitors in the spleen.

Figure 4

Flow cytometry analysis was performed on spleen cells from WT and OI mice. Seven-week old animals (n=5–6) were used to evaluate changes in mature lineages including (A) T cells; (B) B cells; and (C) erythrocyte progenitors. Cohorts of male and female mice at different ages were used to evaluate the frequency of (D) myeloid lineage cells, CD11bhi; and (E) peripheral osteoclast progenitors (OCP), lymphoid− CD11bhi CD115+ Ly6C+. n=4–10. * p<0.05 compared to WT control.