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. Author manuscript; available in PMC: 2018 Jun 14.
Published in final edited form as: N Engl J Med. 2017 Dec 14;377(24):2325–2336. doi: 10.1056/NEJMoa1613773

Table 1.

Demographic and Clinical Characteristics of the Patients and Treatment Details.*

Variable Patient 1 Patient 2 Patient 3 Patient 4 Patient 5
Demographic or clinical characteristic
Age (yr) 61 60 65 62 83
Sex Male Male Male Male Female
Type of cardiomyopathy Nonischemic Ischemic Nonischemic Nonischemic Ischemic
NYHA class IV III IV IV IV
Left ventricular ejection fraction (%) 37 17 22 26 15
No. of previous antiarrhythmic drugs 3 3 3 4 2
No. of previous catheter ablations 1 0 2 4 0
No. of induced episodes of ventricular tachycardia 2 1 0 5 6
No. of episodes of ventricular tachycardia 3 mo before treatment 30 20 5 2210 4312
Treatment
Ablation target region Anterior basal left ventricle Anterolateral basal left ventricle Inferior left ventricle Left ventricle outflow and septum Inferolateral mid left ventricle
blation volume (ml) 51.3 17.3 44.5 53.0 81.0
Treatment time (min) 12 11 14 12 18
Length of hospital stay after treatment (days) 2 1 2 2 1
Antiarrhythmic medication at discharge Amiodarone, mexiletine Amiodarone, mexiletine Amiodarone, mexiletine Amiodarone, mexiletine Amiodarone, mexiletine
No. of episodes of ventricular tachycardia during 6-wk blanking period 0 3 0 355 322
No. of episodes of ventricular tachycardia 10.5 mo after blanking period 3 0 1 0 NA
No. of additional ablation procedures performed by 1 yr 0 0 0 1 at 4 wk NA
Antiarrhythmic medication at 1 yr None None Amiodarone (restarted at 9 mo) None NA
*

NA denotes not applicable because the patient died 3 weeks after treatment, and NYHA New York Heart Association.