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. Author manuscript; available in PMC: 2019 Jan 9.
Published in final edited form as: Cell Metab. 2018 Jan 9;27(1):252–262.e3. doi: 10.1016/j.cmet.2017.12.004

Figure 3. Signal intensity in a Lipodystrophic Rodent Model.

Figure 3

A. A model of inducible lipodystrophy (the “FAT-ATTAC mouse”) selectively loses adipocyte-derived signals upon 18F-FDG injection compared to control. B. SPECT/CT imaging of the FAT-ATTAC lipodystrophic mouse confirms the identity of signals as adipocyte-derived 125I-BMIPP uptake. C. The main metabolically active adipose tissues indicated with blue arrows in an adult mouse model stimulated by β3-adrenergic agonist for 7 days. Blue color label with yellow arrows indicate fat pads that display background signal levels of 18F-FDG-PET/CT and 123I-BMIPP-SPECT/CT. In each case, representative images for n=3 repeats are shown.