Table 2.
Changes in central macular thickness in 29 study eyes from 15 patients with DME
| Time points | Central macular thickness (μm)
|
P-value | |||
|---|---|---|---|---|---|
| Mean (SD) | 95% CI | Crude difference
|
|||
| Mean (SD) | 95% CI | ||||
| Baseline | 460.5 (111.8) | 417.9 to 503.0 | |||
| Intravitreal aflibercept | |||||
| Visit 2 (5 months) | 278.7 (47.7) | 260.6 to 296.9 | −181.8 (120.5) | −227.6 to −135.9 | <0.001 |
| Visit 3 (7 months) | 273.9 (48.5) | 255.4 to 292.4 | −186.6 (108.6) | −227.9 to −145.3 | <0.001 |
| Visit 4 (9 months) | 256.3 (50.3) | 237.2 to 275.5 | −204.1 (124.8) | −251.6 to −156.7 | <0.001 |
| Visit 5 (12 months) | 229.0 (43.8) | 212.3 to 245.6 | −231.5 (126.6) | −279.7 to −183.3 | <0.001 |
| Visit 3 vs visit 2 | −4.8 (45.1) | −22.0 to 12.3 | 0.569 | ||
| Visit 4 vs visit 3 | −17.5 (34.4) | −30.6 to −4.5 | 0.010 | ||
| Visit 5 vs visit 4 | −27.4 (35.0) | −40.7 to −14.1 | 0.001 | ||
Abbreviation: DME, diabetic macular edema.