Table 4. Subgroup analyses for association between LSM and overall postoperative complications.
Group factors | Subgroup | studies | Combined OR | 95%CI | Heterogeneity | P value |
---|---|---|---|---|---|---|
I2 | ||||||
Regions | Asia | 10 | 2.30 | 1.75, 3.04 | 63.2% | 0.004 |
Europe | 3 | 1.12 | 1.00, 1.26 | 78.5% | 0.010 | |
Technique of LSM | MRE | 2 | 2.24 | 1.74, 2.89 | 0.0% | 0.536 |
TE | 7 | 1.30 | 1.11,1.52 | 48.3% | 0.085 | |
SWE | 2 | 1.98 | 1.16, 3.30 | 46.1% | 0.173 | |
ARFI | 2 | 9.74 | 0.39, 240.25 | 76.2% | 0.040 | |
Outcome | Composite complications | 3 | 2.87 | 1.65, 5.00 | 47.3% | 0.150 |
PHLF | 7 | 1.46 | 1.23, 1.74 | 84.7% | 0.000 | |
ascites | 2 | 7.70 | 0.17, 341.88 | 82.9% | 0.000 | |
Hepatic insufficiency | 1 | 19.14 | 2.71, 135.27 | NA | NA | |
Etiology of CLD | Mixed | 11 | 1.74 | 1.42, 2.13 | 87.0% | 0.000 |
Viral hepatitis | 2 | 1.89 | 1.02, 3.49 | 62.0% | 0.105 | |
Stage of fibrosis | The percentage of patients with fibrosis grade F4≥50% | 7 | 1.32 | 1.11, 1.57 | 80.4% | 0.000 |
The percentage of patients with fibrosis grade F4<50% | 6 | 2.20 | 1.60, 3.01 | 64.2% | 0.016 |
LSM, liver stiffness measurement; TE, transient elastography; SWE, shear wave elastography; MRE, magnetic resonance elastography; ARFI, acoustic radio force impulse; CLD, chronic liver diseases.