Table 5. Diagnostic accuracy of ceruloplasmin at the conventional cutoff value in patients with liver, nervous, and mental diseases.
CP(mg/L) | No. of patients diagnosed | Sensitivity(%, 95% CI) | Specificity(%, 95% CI) | PPV(%, 95% CI) | NPV(%, 95% CI) | ||
---|---|---|---|---|---|---|---|
WD | Non-WD | Total | |||||
< 200 | 294 | 463 | 757 | 99.0(98.9–99.1) | 76.4(74.5–78.3) | 38.8(35.3–42.3) | 99.8(99,7–99.9) |
≥ 200 | 3 | 1499 | 1502 | ||||
Total | 297 | 1962 | 2259 |
CP, CI, confidence interval, Ceruloplasmin; WD, Wilson’s disease; PPV, positive predictive value; NPV, negative predictive value.