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. 2018 Jan 11;13(1):e0190887. doi: 10.1371/journal.pone.0190887

Table 5. Diagnostic accuracy of ceruloplasmin at the conventional cutoff value in patients with liver, nervous, and mental diseases.

CP(mg/L) No. of patients diagnosed Sensitivity(%, 95% CI) Specificity(%, 95% CI) PPV(%, 95% CI) NPV(%, 95% CI)
WD Non-WD Total
< 200 294 463 757 99.0(98.9–99.1) 76.4(74.5–78.3) 38.8(35.3–42.3) 99.8(99,7–99.9)
≥ 200 3 1499 1502
Total 297 1962 2259

CP, CI, confidence interval, Ceruloplasmin; WD, Wilson’s disease; PPV, positive predictive value; NPV, negative predictive value.