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. 2018 Jan 11;13(1):e0190887. doi: 10.1371/journal.pone.0190887

Table 6. Proportion of patients with WD with normal ceruloplasmin levels in different regions.

Author Country/time Patients with Wilson’s disease
Total number of patients Patients with normal CP levels
Brewer GJ et al. [24] USA/1992 89 8(11.2%)
Martins da Costa C [25] United Kingdom/1992 17 3(17.6%)
Steindl P et al. [18] Germany/1997 55 15(27.3%)
Merle U et al. [26] Germany/2007 163 19(11.8))
Gheorghe L et al. [27] Romania/2004 55 24(43.6%)
Müller T et al. [28] Austria/2007 35 9(25.7%)
Manolaki N et al. [29] Greece/2008 57 7(12.3%)
Nicastro E et al. [30] Italy/2010 40 2(5.0%)
El-Karaksy H et al. [31] Egypt/2011 54 1(1.9%)
Taly AB et al. [32] India/2007 282 19(6.9%)
Rukunuzzaman MD [33] Bangladesh/2015 100 27(27.0%)
Lee BH et al. [21] Korea/2011 237 0(0.0%)
Mak CM et al. [4] Hong Kong/2008 57 1(1.8%)
Liu Y et al. [23] China/2015 77 2(2.6%)
Feng L et al. [22] China/2016 126 0(0.0%)
This study China/2017 297 3(1.0%)