Table 1. Characteristics of the included studies in alphabetical order.
| Primary Studies | GD | FS | AS | NW | WS | WD | MW | MP | MA | PC | NT |
|---|---|---|---|---|---|---|---|---|---|---|---|
| [42] Abegão 2015 | SA | NFS | RL | 12 | 50.2 | FT | Punch | DS | - | NR | 2 |
| Brazil | (rabbit) | ||||||||||
| [43] Al-Bayati 2013 | AS | NS | NRL | 40 | 900.0 | FT | Blade | DS | CaCl2 | < | 1 |
| Iraq | (goat) | ||||||||||
| [44] Barrionuevo 2015 | SA | NFS | RL | 12 | 50.2 | FT | Punch | DS | CG | NR | 1 |
| Brazil | (rabbit) | ||||||||||
| [45] Bauer 2009 | SA | NS | RL | 8 | 19.6 | FT 2mm | Punch | SS | CaCl2 | < | 1 |
| Brazil | (rat) | ||||||||||
| [46] Blanton 2009 | NA | P | NRL | 48 | 150.0 | FT 7.9mm | Blade | SS | T/TP CaCl2 |
< | 1 |
| USA | (pig) | ep,de,sc | |||||||||
| [47] De Souza 2015 | SA | NP | NRL | 28 | 625.0 | FT | Blade | DS | - | < | 1 |
| Brazil | (horse) | ep,de,sc | |||||||||
| [48] Dionyssiou 2013 | EU | P | RL | 40 | 400.0 | FT | Blade | SS | - | ≥ | 1 |
| Greece | (rabbit) | ||||||||||
| [49] Hadad 2010 | NA | P | NRL | 36 | 150.0 | FT 4mm | - | SS | T/TP CaCl2 |
< | 1 |
| USA | (pig) | ||||||||||
| [50] Jee 2016 | AS | NS | NRL | 24 | 28.3 | FT | Punch | SS | - | ≥ | 2 |
| Korea | (dog) | ep,de | |||||||||
| [51] Karayannop. 2015 | EU | P | NRL | 36 | 400.0 | FT | - | SS | - | ≥ | 1 |
| Greece | (dog) | ||||||||||
| [52] Lee 2008 | NA | NP | RL | 30 | 625.0 | FT | Blade | SS | T/TP CaCl2 |
NR | 1 |
| USA | (rabbit) | ep,de,sc | |||||||||
| [53] Monteiro 2009 | EU | NP | NRL | 24 | 625.0 | FT | Blade | SS | T/TP CaCl2 |
NR | 2 |
| France | (horse) | ep,de,sc | |||||||||
| [54] Nisbet 2009 | AS | NS | RL | 30 | 225.0 | FT | Blade | DS | T/TP CaCl2 |
≥ | 2 |
| Turkey | (rabbit) | ep,de,sc | |||||||||
| [55] Notodihardjo 2014 | AS | NP | RL | 180 | 28.3 | FT | Punch | DS | CaCl2 | ≥ | 1 |
| Japan | (mouse) | ep,de,sc | |||||||||
| [30] Sardari 2011 | AS | NP | NRL | 30 | 400.0 | FT | - | DS | T/TP CaCl2 |
< | 2 |
| Iran | (dog) | ||||||||||
| [56] Vermeulen 2009 | EU | NS | NRL | 21 | 400.0 | FT 1cm | Blade | DS | T | NR | 1 |
| Belgium | (pig) | ep,de,sc | |||||||||
| [57] Yan 2007 | NA | P | NRL | 48 | 226.9 | FT 5mm | Punch | DS | T/TP CaCl2 |
NR | 1 |
| USA | (pig) | ||||||||||
| [58] Yang 2011 | Asia | NP | RL | 14 | 400.0 | FT | Scissor | DS | - | NR | 1 |
| Korea | (mouse) | ep,de,sc |
GD: Geographical distribution; SA: SouthAmerica; NA: NorthAmerica; EU: Europe; AS: Asia; FS: Funding source; P: for profit funding; NP: for non-profit funding; NFS: no-funding statement; NS: no statement regarding the funding source; AS: Animal species; RL: rodent/lagomorph mammals; NRL: non-rodent/lagomorph mammals; NW: Number of wounds; WS: Initial wound size (mm2); WD: Wound depth; FT: full-thickness; ep: epidermidis; de: dermis; sc: subcutaneous tissue; MW: Method of wounding; MP: Method of PRP production; SS: single spin; DS: double spin; MA: Method of PRP Activation; CG: Calcium Gluconate; T: Thrombin; TP: Thromboplastin; PC: Platelet concentration; <: platelet concentration < 106 plt/microL; ≥: platelet concentration ≥ 106 plt/microL; NR: not reported. NT: Number of treatments