Table 1. Summary descriptive data for LBC1936.
| Full sample | Individuals with age 70 expression data | Individuals with age 70 and 76 expression data | ||||
|---|---|---|---|---|---|---|
| Variable | Mean (SD, range) | N | Mean (SD, range) | N | Mean (SD, range) | N |
| Age (years) | 69.5 (0.8, 67.6-71.3) | 1091 | 69.5 (0.8, 67.6-71.3) | 781 | 69.5 (0.8, 67.6-71.3) | 434 |
| gf | 0.0 (1.0, −3.5-2.9) | 1072 | −0.005 (0.1, −3.0-2.9) | 767 | 0.1 (0.1, −3.0-2.9) | 429 |
| IQ change | 0.006 (0.9, −5.6-4.4) | 1016 | 0.005 (1.0, −5.6-4.4) | 726 | 0.05 (0.9, −4.0-4.4) | 404 |
| 6m walk time (s) | 3.8 (1.1, 1.1-11.0) | 1084 | 3.8 (1.1, 1.1-10.9) | 778 | 3.7 (0.9, 1.1-8.8) | 433 |
| Grip strength (Kg) | 29.0 (10.2, 2-60) | 1066 | 29.4 (10.2, 4-60) | 768 | 30.2 (10.0, 11-60) | 427 |
| FEV1 (L) | 2.4 (0.7, 0.5-5.1) | 1085 | 2.4 (0.7, 0.5-5.1) | 780 | 2.5 (0.7, 0.7-4.3) | 434 |
| Fibrinogen (g/L) | 3.3 (0.6, 1.6-6.2) | 1052 | 3.3 (0.6, 1.6-6.2) | 769 | 3.2 (0.6, 1.6-5.9) | 428 |
| HbA1c (% total) | 5.9 (0.7, 4.5-11.6) | 1060 | 5.9 (0.7, 4.5-11.6) | 776 | 5.9 (0.7, 4.5-11.6) | 431 |
| Telomere length (kb) | 4.2 (0.6, 2.7-7.1) | 1070 | 4.2 (0.5, 2.8-7.1) | 781 | 4.2 (0.6, 2.8-7.1) | 434 |
| Sex | Male | 548 (50%) | 400 (51%) | 230 (53%) | ||
| Female | 543 (50%) | 381 (49%) | 204 (47%) | |||
| CRP | Normal (0.3 mg/L) | 535 (51%) | 401 (52%) | 244 (57%) | ||
| Elevated (4-10 mg/L) | 399 (38%) | 294 (38%) | 154 (36%) | |||
| Acute (>10 mg/L) | 120 (11%) | 80 (10%) | 34 (8%) | |||
| Smoking status | Current smoker | 125 (12%) | 92 (12%) | 33 (8%) | ||
| Past smoker | 465 (43%) | 325 (42%) | 182 (42%) | |||
| Never smoker | 501 (46%) | 364 (47%) | 219 (51%) | |||
| Mortality status | Alive | 868 (80%) | 627 (80%) | 398 (92%) | ||
| Dead | 223 (20%) | 154 (20%) | 36 (8%) | |||