Cerebral MRI of genetic vascular disorders of the white matter

Figure 2. (A, B) Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Fluid-attenuated inversion recovery (FLAIR) sequence: symmetrical hyperintensities of external capsules, thalami (A), and anterior part of the temporal lobe (B). (C, D) COL4A1 mutation. (C) FLAIR sequence. Right porencephalic cavity. (D) Gradient echo sequence. Numerous microbleeds. (E, F) Leukoencephalopathy with calcifications and cysts. (E) FLAIR sequence. Cystic aspect in the demyelinating area. (F) T1 weighted with gadolinium injection. Enhancement of the cysts by the contrast product. (G, H) Fabry disease. (G) FLAIR sequence. Lacunes and hyperintensities of the white matter involving the external capsules. (H) Gradient echo sequences. Numerous deep microbleeds.