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. Author manuscript; available in PMC: 2019 Feb 7.
Published in final edited form as: J Theor Biol. 2017 Nov 15;438:34–45. doi: 10.1016/j.jtbi.2017.11.010

FIGURE 2.

FIGURE 2

Models Combined into the Integrative Model: (a) The extracellular purinergic metabolism model describing the time response of 100 μM [ATP] addition to human airway surfaces. As in Zuo et al. (2008), the symbols are experimental data, while the solid lines are the reproduced result by the ATP model component in the integrative cell model. (b) The reproduced result of the fluid transport model from Warren et al. (2010): the predictions of 33% hypotonic challenge experimental data from Okada et al. (2006)