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. Author manuscript; available in PMC: 2019 Feb 7.
Published in final edited form as: J Theor Biol. 2017 Nov 15;438:34–45. doi: 10.1016/j.jtbi.2017.11.010

FIGURE 6.

FIGURE 6

Model Simulations of Mechanical Forces and Pharmacologic Maneuvers in NL and CF Airway Epithelia: (a) 12 tests were performed to validate the NL model. The CSS was 0.5 dynes/cm2. Experimental data in Test 1 to 6 is from Tarran et al. (2005), Test 7 to 12 from Tarran et al. (2006). (b) 12 tests were performed to validate the CF model. The CSS was 0.5 dynes/cm2. The CCP was 20 cmH2O. Experimental data in Test 1 to 6 is from Tarran et al. (2005), Test 7 from Button et al. (2007), and Test 8 to 12 from Tarran et al. (2006). The simulation conditions used to mimic the effect of the drugs are listed in Table 1.