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. Author manuscript; available in PMC: 2019 Feb 7.
Published in final edited form as: J Theor Biol. 2017 Nov 15;438:34–45. doi: 10.1016/j.jtbi.2017.11.010

FIGURE 7.

FIGURE 7

Model Simulations of Mechanical Forces – Dependent ATP Release on ASL Height in NL and CF Airway Epithelia: (a) The relationships between the absolute ASL heights and CSS in NL and CF models. (b) The relationships between the absolute ASL heights and CCP in NL and CF models. (c) The relationship between the increase of mucus viscosity and the increase of ASL height in the NL model comparing with experimental data from Button et al. (2013). Also shown is simulation for CF airway epithelia. (d) The relationship between the increase of [ATP] triggered by increasing mechanical forces and the increase of ASL height for NL cells comparing with experimental data of Button et al. (2013). CF simulation is also shown.