Table 3. Recommended influenza vaccine dosage and route, by age, for the 2017–2018 influenza season.

Age group	TIV without adjuvant1 Intramuscular	QIV without adjuvant2 Intramuscular	TIV without adjuvant, high- dose (Fluzone® High-Dose) Intramuscular	MF59-adjuvanted TIV (Fluad Pediatric® or Fluad®) Intramuscular	LAIV (FluMist® Quadrivalent) Intranasal	Number of doses required
6–23 months	0.5 mL3	0.5 mL3	N/A	0.25 mL	N/A	1 or 24
2–8 years	0.5 mL	0.5 mL	N/A	N/A	0.2 mL (0.1 mL per nostril)	1 or 24
9–17 years	0.5 mL	0.5 mL	N/A	N/A	0.2 mL (0.1 mL per nostril)	1
18–59 years	0.5 mL	0.5 mL	N/A	N/A	0.2 mL (0.1 mL per nostril)	1
60–64 years	0.5 mL	0.5 mL	N/A	N/A	N/A	1
65 years and older	0.5 mL	0.5 mL	0.5 mL	0.5 mL	N/A	1

Abbreviations: LAIV, live attenuated influenza vaccine (quadrivalent formulation); N/A, not applicable; QIV, quadrivalent inactivated influenza vaccine; TIV, trivalent inactivated influenza vaccine
¹ Influvac^® 18 years and older, Fluviral^® 6 months and older, Agriflu^® 6 months and older, Vaxigrip^® 6 months and older, Fluzone^® 6 months and older
² Flulaval^® Tetra 6 months and older, and Fluzone^® Quadrivalent 6 months and older
³ This information differs from the product monograph. Published and unpublished evidence suggest moderate improvement in antibody response in infants, without an increase in reactogenicity, with the use of full vaccine doses (0.5 mL) for unadjuvanted inactivated influenza vaccines (37,38). This moderate improvement in antibody response without an increase in reactogenicity is the basis for the full dose recommendation for unadjuvanted inactivated vaccine for all ages. For more information, refer to Statement on Seasonal Influenza Vaccine for 2011–2012 (39)
⁴ Children 6 months to less than 9 years of age who have never received the seasonal influenza vaccine require two doses of influenza vaccine, with a minimum interval of four weeks between doses. Eligible children less than 9 years of age who have properly received one or more doses of seasonal influenza vaccine in the past should receive one dose per influenza vaccination season thereafter