Table 5. Final multivariate logistic regression models predicting occurrence of Lyme disease clinical manifestations in patients, Canada, 2009–2015 (n=1,657).

Explanatory variables	Estimate	Odds ratio	CI at 95%	Wald test	P value
Early Lyme disease (erythema migrans)
10–19 years vs 0–9 years	−0.490	0.613	0.378–0.994	3.932	0.047
30–39 years vs 0–9 years	−0.513	0.599	0.378–0.950	4.753	0.029
Early disseminated (neurologic and cardiac symptoms; multiple erythema migrans)
Male vs female	−0.272	0.762	0.585–0.992	4.083	0.043
20–29 years vs 0–9 years	0.678	1.969	1.071–3.623	4.751	0.029
Year 2010 vs 2015	−0.555	0.574	0.392–0.841	8.137	0.004
Late disseminated (arthritis)
Male vs female	0.246	1.279	1.031–1.586	5.012	0.025
75+ years vs 0–14 years	−0.691	0.501	0.283–0.888	5.604	0.018
Year 2011 vs 2015	0.565	1.759	1.221–2.533	9.200	0.002
Year 2010 vs 2015	0.774	2.168	1.630–2.883	28.777	0.000
Year 2009 vs 2015	0.472	1.603	1.168–2.199	8.554	0.003

Abbreviations: CI, confidence interval