Renal mRNA (A) and protein (B) expressions of (Pro)renin receptor (PRR), mRNA (C) and protein (D) expressions of Tumor necrosis factor- α (TNF-α), mRNA (E) and protein (F) expressions of COX-2, phosphorylation of p-NFκB (G) and total expression of NFκB (H) in Non-clip kidney (NCK, RK) vs clipped kidney (CK, LK) in sham and 2K1C rats following scramble shRNA and PRR shRNA administration in CK. mRNA normalized to β-actin, representative blots (top), quantitative results normalized to β-actin. Data presented as mean ± SEM, *p<0.05 vs sham and #p<0.05 vs 2K1C+ scramble shRNA.