Table 2.
SNPs associated with lipid, cafestol, kahweol contents and cafestol/kahweol ratio detected by three different GWAS methods (mrMLM, ISIS EM-BLASSO, pLARmEB).
| Trait | SNP | mrMLM(p-value) | ISIS EM-BLASSO(LOD value) | pLARmEB(p-value) |
|---|---|---|---|---|
| Lipid | S1_24382872 | 6.0 e-04 | ||
| Lipid | S2_14041151 | 1.3 e-03 | ||
| Lipid | S2_20725291 | 2.0 e-04 | ||
| Lipid | S6_36332719 | 2.56 | ||
| Lipid | S8_25559761 | 3.27 e-05 | 3.56 | |
| Cafestol | S3_7990620 | 4.0 e-04 | ||
| Cafestol | S6_7853861 | 2.33 | 1.0 e-04 | |
| Cafestol | S11_29778697 | 1.77 e-06 | 3.64 | 1.49 e-06 |
| Cafestol | S11_30776239 | 3.77 | ||
| Kahweol | S2_45775221 | 3.11 e-06 | 5.11 | 1.99 e-06 |
| Kahweol | S4_5260584 | 3.1 | ||
| Kahweol | S8_17996908 | 9.0 e-04 | ||
| Ratio | S2_15335083 | 4.83 | 2.73 e-05 | |
| Ratio | S2_15335417 | 2.24 | 2.73 e-05 | |
| Ratio | S2_48526210 | 7.7 | 8.02 e-09 | |
| Ratio | S4_3861777 | 7 e-04 | ||
| Ratio | S5_27320598 | 2.18 | ||
| Ratio | S5_3863439 | 1.1 e-03 | ||
| Ratio | S6_12529278 | 6.96 e-06 | 1.34 e-05 | |
| Ratio | S7_5138106 | 4.44 | 3.62 e-07 | |
| Ratio | S11_17488418 | 5.86 | 4.16 e-06 |