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. 2018 Jan 11;9:162. doi: 10.1038/s41467-017-02614-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Relative value signals in the activity of mOFC neurons. a Rasters and histograms of an example mOFC neuron modulated by the relative value of options. The activity aligned at cue onset during free choice trials was shown for 20 lottery pairs (four PBs times five LPs, 200 trials). Black dots in the histograms indicate raster of spikes. Gray bars indicate the cue period to estimate the neuronal firing rates shown in b. SAC indicate approximate time of saccade onset. b Activity plot of the mOFC neuron in a against the expected values of risky (EVr) and safe option (EVs). Error bars indicate s.e.m. The neuron showed positive and negative regression coefficients for EVr and EVs (EVr+EVs− type, EVr, 0.042, EVs, −0.048, AIC = 1283), respectively. c Activity histogram of 15 mOFC neurons modulated by relative values of risk and safe options during cue period (EVr+EVs– type). Activity in each of four payoff blocks (PB1–4) is shown for the five types of lottery pairs (LP1–5). d Percentage of mOFC neurons modulated by relative values during three task periods. Gray indicates activity showing the positive and negative regression coefficients for EVr and EVs, respectively (EVr+EVs− type). White indicates activity showing negative and positive regression coefficients for EVr and EVs, respectively (EVr−EVs+ type)