Table 4.
Acute toxicity during IMRT of both groups.
| Grade | 0 | 1-2 | 3-4 | P* |
|---|---|---|---|---|
| Leucopenia | 0.7464 | |||
| CCRT | 29 (23%) | 91 (72%) | 7 (06%) | |
| NeoCT-RT | 26 (20%) | 98 (76%) | 5 (04%) | |
| Anemia | 0.0931 | |||
| CCRT | 72 (57%) | 52 (41%) | 3 (02%) | |
| NeoCT-RT | 44 (34%) | 75 (58%) | 10 (08%) | |
| Thrombocytopenia | 1.0000 | |||
| CCRT | 121 (95%) | 5 (04%) | 1 (01%) | |
| NeoCT-RT | 122 (95%) | 6 (05%) | 1 (01%) | |
| Mucositis | <0.0001 | |||
| CCRT | 0 | 57 (45%) | 70 (55%) | |
| NeoCT-RT | 6 (05%) | 103 (80%) | 20 (16%) | |
| Neck dermatitis | 0.0041 | |||
| CCRT | 0 | 87 (69%) | 40 (31%) | |
| NeoCT-RT | 0 | 109 (84%) | 20 (16%) | |
| Vomiting | <0.0001 | |||
| CCRT | 10 (08%) | 88 (69%) | 29 (23%) | |
| NeoCT-RT | 117 (91%) | 12 (09%) | 0 | |
| Weight loss | 0.0068 | |||
| CCRT | 2 (02%) | 118 (93%) | 7 (06%) | |
| NeoCT-RT | 26 (20%) | 103 (80%) | 0 | |
Abbreviations: IMRT, intensity-modulated radiotherapy; CCRT, concurrent chemoradiotherapy; NeoCT, neoadjuvant chemotherapy; RT, radiotherapy.
*P-values were calculated by comparing the incidence of the grade 3/4 toxicities between both groups.