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. 2018 Jan 11;8:546. doi: 10.1038/s41598-017-18699-8

Figure 1.

Figure 1

Characterisation of existing Skin Proteomes. To assess the existing proteomics data available we downloaded the contents of two databases, Pax.DB and Human Protein Atlas (HPA) in addition to the largest single skin proteomics paper Bliss 2016, below is a list of the 56 common proteins to all of the analysed proteomes. (a) Shows the number of proteins in each database and any consensus between the data. (b) Using GO terms the corresponding data was assessed for the subcellular location of each protein listed in the databases; here we show there is a general consensus with regards to subcellular location of proteins but that the absolute values are disparate between the databases. What is clear from the analysis is the obvious lack of proteins commonly associated with the skin, (c) here we show some key examples of proteins not listed in the 56 consensus proteins and their locations within the skin.