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. 2018 Jan 11;8:435. doi: 10.1038/s41598-017-18877-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Principal coordinate analysis (PCoA) of 16S metagenomic data of bacterial species in human faecal samples obtained from a human intervention study. Four human volunteers (designated as F26, M37, M38, and M39) participated in this study. In one subject, two faecal samples (designated as washout-1 (plot 1) and washout-2 (plot 3)) were collected after the subjects drank water for 14 days and another two faecal samples (designated as αCD (plot 2) and DEX (plot 4)) were collected after the subjects consumed α-cyclodextrin or indigestible dextrin, respectively, for seven days. In addition, PCoA plots, which were obtained from the KUHIMM without prebiotics (CUL (plot b)) and with indigestible dextrin (DEX (plot c)) or α-cyclodextrin (αCD (plot d)) (already shown in Fig. 2), are also presented. Faecal samples from the subjects participating in the human intervention study were used to inoculate the cultures in the KUHIMM.