Table 1.
Non-coding RNA partners in ceRNA regulatory mechanism
| Non-coding RNA | miRNA | mRNA targets of miRNA | Function | Human disease, species, etc. | References |
|---|---|---|---|---|---|
| Pseudogene | |||||
| PTENP1 | miR-20a, miR-19b, miR-21, miR-26a and miR-214 | PTEN | Tumor suppression | Human | [20] |
| KRAS1P | miR-143 and let-7 family | KRAS | Carcinogenesis | Human | [20] |
| PTENP1 | miR-17, miR-19b and miR-20a, | PTEN | Tumor suppression | Hepatocellular carcinoma | [21] |
| Pbcas4 | miR-185 | Bcl2, Il17rd, Pnpla3, Shisa7 and Tapbp | Mouse and human | [22] | |
| HMGA1P7 | miR-15, miR-16, miR-214 and miR-761 | H19 and Igf2 | Carcinogenesis | Mouse | [23] |
| Small ncRNA | |||||
| HSURs 1 and 2 | miR-142-3p, miR-27 and miR-16 | FOXO1 | Viral infection | Human T cells | [24] |
| Circular RNA | |||||
| ciRS-7 (CDR1as) | miR-7 | Brain development | Human and mouse | [40, 41] | |
| Myrip | Diabetes suppression | Human and mouse | [42] | ||
| Sry | miR-138 | Mouse | [40] | ||
| lncRpa and circRar1 | miR-671 | CASP8 and P38 | Apoptosis | Mouse neuronal cell | [110] |
| circHIPK3 | miR-124 | IL6R and DLX2 | Carcinogenesis | Human | [43] |
| circRNA-CER | miR-136 | MMP13 | Osteoarthritis | Human chondrocytes | [111] |
| lncRNA | |||||
| IPS1 | miR-399 | PHO2 | Plant growth | Arabidopsis thaliana | [19] |
| linc-ROR | miR-145 | Oct4, Nanog and Sox2 | Self-renewing | Human embryonic stem cell | [28] |
| miR-205 | ZEB2 | Carcinogenesis | Breast cancer | [26] | |
| HOTAIR | miR-331-3p | HER2 | Carcinogenesis | Gastric cancer | [32] |
| miR-141 | SKA2 | Carcinogenesis | Glioma | [112] | |
| MALAT1 | miR-124 | GRB2 | Carcinogenesis | Cervical cancer | [113] |
| H19 | miR-106a | CDKN1A, DICER1, RB1, ARID4B, ANKRD52 and FAM102A | Myoblast differentiation | Human myoblast | [38] |
| miR-138 and miR-200a | Vimentin, ZEB1, and ZEB2 | Carcinogenesis | Hepatocellular carcinoma | [108] | |
| miR-200b/c and let-7b | Git2 and Cyth3 | Carcinogenesis | Breast cancer | [114] | |
| HULC | miR-372 | PRKACB | Carcinogenesis | Liver cancer | [44] |
| linc-MD1 | miR-133 and miR-135 | MAML1 and MEF2C | Myoblasts differentiation | Mouse and human myoblasts | [45] |
| BACE1-AS | miR-485-5p | BACE1 | Alzheimer’s disease | Human brain | [46] |
| lncRNA-ATB | miR-200 family | ZEB1 and ZEB2 | Carcinogenesis | Hepatocellular carcinoma | [47] |
| CCAT1 | miR-218-5p | Bmi1 | Carcinogenesis | Gallbladder cancer | [115] |
| ZFAS1 | miR-150 | ZEB1, MMP14 and MMP16 | Carcinogenesis | Hepatocellular carcinoma | [116] |
| lncRNA-BGL3 | miR-17, miR-93, miR-20a, miR-20b, miR-106a and miR-106b | PTEN | Tumor suppression | Leukemia | [117] |