Table 1. Patient characteristics.

Characteristic	Number (%)
Age
Median (range)	67 (54–79)
Sex
Male	5 (38%)
Female	8 (62%)
Smoking history
Never	7 (54%)
Former/current	6/0 (46%)
Histology
Adenocarcinoma	13 (100%)
Primary EGFR-sensitive mutations
Del-19	10 (77%)
L858R	3 (23%)
Prior regimens
Median (range)	4 (3–8)
Number of prior EGFR-TKIs
Median (range)	2 (1–3)
Prior whole-brain radiotherapy
Irradiated	3 (23%)
None	10 (77%)
Anti-brain edema therapy
Steroids/glycerol	7 (54%)
None	6 (46%)

Abbreviations: EGFR=epidermal growth factor receptor; TKI=tyrosine kinase inhibitor.