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Xantohumol suppressed the secretion of VEGF and IL‐8 in pancreatic cancer cell lines. Pancreatic cancer cell lines (BxPC‐3 and AsPC‐1) were treated with xanthohumol at the indicated concentrations for 72 h, and the supernatants were then collected. The concentrations of secreted VEGF and IL‐8 were measured using ELISA. Values are expressed as means ± SD (n = 3; *P < .05; **P < .01 compared with the control in all cell lines). C, control
