Figure 5.
Xanthohumol inhibited tumor growth in a subcutaneous xenograft model of pancreatic cancer. BxPC‐3 cells (5 × 106 cells in 100 μL Hank's balanced salt solution) were injected subcutaneously, and tumors were developed. Mice were divided into 2 groups: untreated (group I) and treated with xanthohumol (10 mg/kg, ip, injection, weekly; group II). A, Images of mice and solid tumors removed from each group: (i) control and (ii) xanthohumol. B, Measurement of tumor volumes in each group once per week. C, Measurement of tumor weights in nude mice after sacrifice. D, Measurement of body weights in each group once per week. Values in (B), (C) and (D) represent the means ± SD of each group (n = 5; *P < .05, **P < .01 compared with the untreated group). NS, not significant