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. 2017 Nov 27;153(2):133–144. doi: 10.1111/imm.12857

Figure 7.

Figure 7

Analysis of the T‐cell receptor‐β variable (TRBV) gene segment usage. (a) Unweighted and weighted analysis of TRBV gene segment usage in old (n = 8) and young (n = 8) C57BL/6J mouse peripheral blood samples. (b) CD4/CD8 ratio in the young (n = 8) and old (n = 8) C57BL/6J mice. Two‐tailed Mann–Whitney test. (c) Unweighted and weighted analysis of TRBV gene segment usage in sorted thymic and splenic naive CD4 and CD8 T cells of 1‐year‐old C57BL/6J mice (n = 5). (d) Jensen–Shannon divergence of TRBV gene segment usage distributions in sorted thymic and splenic naive CD4 and CD8 T cells of 1‐year‐old C57BL/6J mice (n = 5).