Table 1.

Characteristics of Study Subjects by Research Site

Research Site*	No. of Subjects	Consortium Lung Phenotype† (Mean ± SD)	Age at Consortium Lung Phenotype† (yr) (Median; Range)	Male Sex (%)	BMI (Mean ± SD)	Pseudomonas aeruginosa Infection‡ (%)	CFRD§ (%)	European|| (%)	Phe508del Homozygous (%)
CWRU	38	0.9 ± 0.9	24.3; 11.4–49.2	46	21.8 ± 3.3	90	48	98	79
JHU	17	1.2 ± 0.8	27.1; 18.3–47.3	49	22.2 ± 3.7	92	30	100	77
TOR	35	0.8 ± 0.6	23.1; 10.4–42.6	63	22.0 ± 3.8	78	23	97	100
UNC	44	0.7 ± 0.8	23.8; 11.6–49.5	53	21.9 ± 3.8	91	35	100	100
Total	134	0.8 ± 0.8	26.5; 10.4–49.5	52	21.8 ± 3.3	86	35	99	91

Definition of abbreviations: BMI = body mass index; CFRD = cystic fibrosis–related diabetes; CWRU = Case Western Reserve University; JHU = Johns Hopkins University; KNoRMA = Kulich Normal Residual Mortality Adjusted; TOR = University of Toronto; UNC = University of North Carolina.

^*See Methods section of online supplement for participating sites and enrollment information.

^†Subjects were defined by the quantitative Consortium lung phenotype (KNoRMA) value (8).

^‡Positive lower respiratory culture within 2 years preceding study enrollment; percentage noted is based on data available for 94 subjects.

^§CFRD percentage noted is based on data available for 117 subjects.

^||Based on self-identified ancestry and principal component analysis via SNP genotypes.