Table 1.

Products used in cartilage tissue engineering that have either European Medicines Agency (EMA) or Food and Drug Administration (FDA) approval

Trade name	Marketing company	Product components	Regenerative triad elements	Approval authority	Date of approval
		Polyethylene glycol (PEG)	Scaffold	FDA	Pre 2010
		Polylactic acid (PLA)	Scaffold	FDA	Pre 2010
		Polylactide‐glycolic acid (PLGA)	Scaffold	FDA	Pre 2010
Carticel®	Vericel	Autologous chondrocytes	Cells	FDA	Pre 2010
SaluCartilage™	Salumedica	Poly‐vinyl alcohol (PVA) hydrogel	Scaffold	EMA, FDA	Pre 2010
CaReS®	Arthrokinetics	Autologous chondrocytes and type 1 collagen	Cells and scaffold	EMA	Pre 2010
MACI®	Vericel	Autologous chondrocytes and porcine collagen	Cells and scaffold	FDA	Post 2010
BST‐Cargel®	Smith & Nephew	Chitosan polysaccharide	Liquid scaffold	EMA	Post 2010
GelrinC	Reagentis Biomaterials	Polyethylene glycol diacrylate (PEG‐DA) and denatured fibrinogen, crosslinked with UVA light	Scaffold	EMA	Post 2010
Agili‐C™	CartiHeal	Aragonite and hyaluronic acid	Biphasic scaffold	EMA	Post 2010